{"id":10663,"date":"2025-03-20T00:41:00","date_gmt":"2025-03-20T00:41:00","guid":{"rendered":"http:\/\/cannabis.net\/blog\/medical\/cbg-for-cancer-and-pain-this-cannabinoid-might-just-be-the-next-big-thing-in-cannabis"},"modified":"2025-03-20T00:41:00","modified_gmt":"2025-03-20T00:41:00","slug":"cbg-for-cancer-and-pain-this-cannabinoid-might-just-be-the-next-big-thing-in-cannabis","status":"publish","type":"post","link":"https:\/\/cannitrol.com\/blog\/cbg-for-cancer-and-pain-this-cannabinoid-might-just-be-the-next-big-thing-in-cannabis\/","title":{"rendered":"CBG for Cancer and Pain? This Cannabinoid Might Just Be the Next Big Thing in Cannabis"},"content":{"rendered":"<div id=\"wp_fb_like_button\" style=\"margin:5px 0 5px 5px;float:right;height:100px;\"><script src=\"http:\/\/connect.facebook.net\/en_US\/all.js#xfbml=1\"><\/script><fb:like href=\"https:\/\/cannitrol.com\/blog\/cbg-for-cancer-and-pain-this-cannabinoid-might-just-be-the-next-big-thing-in-cannabis\/\" send=\"true\" layout=\"standard\" width=\"450\" show_faces=\"false\" font=\"arial\" action=\"like\" colorscheme=\"light\"><\/fb:like><\/div><p><img src=\"https:\/\/cannitrol.com\/blog\/wp-content\/uploads\/2025\/03\/cbg-for-cancer-and-pain-this-cannabinoid-might-just-be-the-next-big-thing-in-cannabis.jpg\"><\/p>\n<p><img alt=\"CBG for pain and cancer\" src=\"https:\/\/cannitrol.com\/blog\/wp-content\/uploads\/2025\/03\/cbg-for-cancer-and-pain-this-cannabinoid-might-just-be-the-next-big-thing-in-cannabis-1.jpg\" \/><\/p>\n<p>CBG For Cancer And Pain?<br \/>This Cannabinoid Might Just Be The Next Big Thing In Marijuana<\/p>\n<p><a href=\"https:\/\/cannabis.net\/blog\/medical\/what-is-cbg\">Cannabigerol (CBG)<\/a> might be considered a minor cannabinoid, but it\u2019s certainly garnering much more attention recently and it isn\u2019t surprising why!<\/p>\n<p>CBG, also known as the <a href=\"https:\/\/cannabis.net\/blog\/medical\/study-says-cbg-treats-inflammation-and-oxidative-stress\">mother of all cannabinoids<\/a>, is a lesser-known cannabinoid compared to its more famous siblings: CBD and THC. But as it occurs as a precursor to CBD and THC, enzymes convert cannabigerolic acid into these other cannabinoids. As a result, mature cannabis plants only contain trace amounts of CBG in them. However, researchers have found that there\u2019s a good reason or two to use CBG for health and wellness.<\/p>\n<p><strong>Studies Show Potential Anti-Cancer Mechanisms In CBG<\/strong><\/p>\n<p>According to a recent article in <a href=\"https:\/\/www.marijuanamoment.net\/lesser-known-marijuana-component-cbg-is-a-promising-therapeutic-agent-with-potential-to-treat-cancer-and-pain-study-says\/\">Marijuana Moment<\/a>, scientists found that CBG could even have potential benefits for treating cancer, pain, and inflammatory conditions.\u00a0 <a href=\"https:\/\/www.mdpi.com\/1420-3049\/29\/22\/5471\">Through a review of studies, researchers<\/a> from China and the United States worked together to review the effects of the cannabinoid, as well as its impacts on the body.<\/p>\n<p>\u201cCBG has emerged as a potential therapeutic agent with a diverse range of effects,\u201d reads the study. \u201cAlthough this research on CBG is still in its early stages, its unique molecular mechanism and promising therapeutic profile warrant further exploration,\u201d they said.<\/p>\n<p>\u201cAs research progresses, <a href=\"https:\/\/cannabis.net\/blog\/medical\/how-effective-is-cbg-for-pain-relief\">CBG presents a promising therapeutic agent<\/a> with a unique molecular profile and a broad spectrum of potential benefits,\u201d said the researchers. \u201cAs we deepen our understanding of CBG, it may lead to breakthroughs in treating complex conditions, ultimately improving patient outcomes and expanding the scope of cannabinoid-based medicine,\u201d it wrote.<\/p>\n<p>Researchers also found that it could be beneficial in <a href=\"https:\/\/cannabis.net\/blog\/medical\/cannabis-strains-vs.-chronic-pain\">reducing pain.<\/a> They observed that administering CBG was helpful in decreasing pain sensitivity on animal subjects. \u201cThis research unveils a potential mechanism for CBG\u2019s indirect neuroprotective effects. By reducing pain signaling in the nervous system, CBG might offer relief from chronic pain conditions,\u201d said the researchers. \u201cThis finding adds to the growing body of evidence suggesting CBG\u2019s potential role in protecting the nervous system by managing pain.\u201d<\/p>\n<p>In <a href=\"https:\/\/link.springer.com\/article\/10.1007\/s12672-024-01356-8\">another study<\/a> also from 2024, scientists acknowledge the anti-cancer properties of cannabinoids including CBD, THC, and even CBG. \u201cCannabinoids, including 9-THC, CBD, and CBG exhibit significant anticancer activities such as apoptosis induction, autophagy stimulation, cell cycle arrest, anti-proliferation, anti-angiogenesis, and metastasis inhibition,\u201d wrote the report.<\/p>\n<p>\u201cClinical trials have demonstrated cannabinoids\u2019 efficacy in tumor regression and health improvement in palliative care,\u201d they wrote. That said, the researchers acknowledge that more work needs to be done to understand the cannabinoids\u2019 mechanism of action for these. \u201cDespite the evident anti-cancer properties of cannabinoids from numerous experimental results, the exact mechanisms of action still require extensive research,\u201d they said.<\/p>\n<p>These, and several other studies, note the promising efficacy and safety of CBG for treating cancer especially when used in conjunction with other cannabinoids. Typically, these studies also look at CBD and THC. After all, it\u2019s a well-known fact that the entourage effect is more powerful than isolating cannabinoids alone. It refers to the synergistic interactions between cannabinoids as well as the other compounds found in marijuana.<\/p>\n<p>Simply put, the entourage effect states that the therapeutic benefits of cannabinoids are much more powerful when they all work together instead of just one alone. In these studies, we can see that CBG may be a potent anti-cancer compound particularly when given to patients alongside CBD and THC.<\/p>\n<p>CBG For Colorectal Cancer<\/p>\n<p>Meanwhile, <a href=\"https:\/\/academic.oup.com\/carcin\/article\/35\/12\/2787\/335166\">another study<\/a> from 2014 highlighted CBG\u2019s potential for treating <a href=\"https:\/\/cannabis.net\/blog\/medical\/does-medical-cannabis-help-with-colorectal-cancer\">colorectal cancer<\/a>. The study, which was published in the medical journal, Carcinogenesis, discusses the powerful action observed where CBG\u00a0 promotes programmed cell death (apoptosis). In addition, the scientists observed that CBG was also beneficial in improving oxidative stress response while reducing the cancer cell growth.<\/p>\n<p>CBG with Other Cannabinoids For Breast Cancer<\/p>\n<p>In a <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29940172\/\">2018 study<\/a>, researchers analyzed the anti-tumor activity observed in different types of cancer when exposed to various botanical preparations containing cannabinoids such as THC, THCA, and CBG. They found that the preparations containing all these cannabinoids were much more powerful than those containing just THC for <a href=\"https:\/\/cannabis.net\/blog\/medical\/cannabis-for-breast-cancer\">breast cancer<\/a>, of course due to the entourage effect. The researchers concluded that these drug preparations were indeed more powerful than just simply pure cannabinoids.<\/p>\n<p>CBG For Tumors<\/p>\n<p><a href=\"https:\/\/cannabis.net\/blog\/medical\/cannabis-for-glioma-brain-cancer\">Glioblastoma<\/a> is one of the <a href=\"https:\/\/www.aans.org\/patients\/conditions-treatments\/glioblastoma-multiforme\/#:~:text=Prevalence%20and%20Incidence,of%203.21%20per%20100%2C000%20population\">most difficult cancers<\/a> to treat. It\u2019s also extremely aggressive, and patients with this form of cancer are given just about a year more to live. Since glioblastoma is so difficult to treat, it usually requires radiation, chemotherapy, as well as surgery.<\/p>\n<p>There have been several studies pointing to the numerous benefits of THC for glioblastoma, but now scientists see the potential of CBG as well. In February 2021, the results of a <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7914500\/#B30-cells-10-00340\">significant study<\/a> on CBG and glioblastoma was released. Researchers from the University Medical Centre Ljubljana studied biopsied glioblastoma tumor cells as well as glioblastoma stem cells from patients with this type of cancer. For this study, the researchers analyzed the anti-tumor properties of different cannabinoids and doses, including THC, CBD, and CBG. They also compared the results of cannabinoids with temozolomide.<\/p>\n<p>They found that CBG was effective in making glioblastoma more responsive to chemotherapy, when used alone or together with CBD. As a result, this yielded better rates of apoptosis. Furthermore, they found that combining CBD and THC was effective in reducing the viability of both cell types and promoted a significant degree of apoptosis among glioblastoma cells.<\/p>\n<p>They also found that CBG worked to inhibit as much as 90% of invasive glioblastoma cell tendril development, whereas chemotherapy drugs only worked for 50%. These are extremely important findings since glioblastoma cell tendrils are extremely invasive, a major reason why this cancer is nearly impossible to treat. \u201cTHC has little added value in combined-cannabinoid glioblastoma treatment, suggesting that this psychotropic cannabinoid should be replaced with CBG in future clinical studies of glioblastoma therapy,\u201d they added.<\/p>\n<p>CONCLUSION<br \/>\u00a0<\/p>\n<p>CBG should no longer be viewed as a \u2018minor cannabinoid\u2019. With all its potential health benefits, especially in the realm of cancer, this life-saving cannabinoid can help improve the prognosis and lifespan for thousands of cancer patients worldwide. We hope to see more studies cementing its therapeutic applications for cancer.<\/p>\n<h3><strong>CBG FOR PAIN RELIEF, READ ON&#8230;<\/strong><\/h3>\n<p><strong><a href=\"https:\/\/cannabis.net\/blog\/medical\/how-effective-is-cbg-for-pain-relief\"><img alt=\"CBG FOR CANCER PAIN\" src=\"https:\/\/cannitrol.com\/blog\/wp-content\/uploads\/2025\/03\/cbg-for-cancer-and-pain-this-cannabinoid-might-just-be-the-next-big-thing-in-cannabis-2.jpg\" \/><\/a><\/strong><\/p>\n<p><a href=\"https:\/\/cannabis.net\/blog\/medical\/how-effective-is-cbg-for-pain-relief\"><strong>WHY IS CBG BEING TESTED FOR PAIN RELIEF MEDS?<\/strong><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>CBG For Cancer And Pain?This Cannabinoid Might Just Be The Next Big Thing In Marijuana Cannabigerol (CBG) might be considered a minor cannabinoid, but it\u2019s certainly garnering much more attention recently and it isn\u2019t surprising why! CBG, also known as the mother of all cannabinoids, is a lesser-known cannabinoid compared to its more famous siblings: [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[9,1,3,61,1736],"tags":[],"_links":{"self":[{"href":"https:\/\/cannitrol.com\/blog\/wp-json\/wp\/v2\/posts\/10663"}],"collection":[{"href":"https:\/\/cannitrol.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cannitrol.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cannitrol.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cannitrol.com\/blog\/wp-json\/wp\/v2\/comments?post=10663"}],"version-history":[{"count":0,"href":"https:\/\/cannitrol.com\/blog\/wp-json\/wp\/v2\/posts\/10663\/revisions"}],"wp:attachment":[{"href":"https:\/\/cannitrol.com\/blog\/wp-json\/wp\/v2\/media?parent=10663"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cannitrol.com\/blog\/wp-json\/wp\/v2\/categories?post=10663"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cannitrol.com\/blog\/wp-json\/wp\/v2\/tags?post=10663"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}