Marijuana And Bronchial asthma
Character, a peer-examined scientific journal, mentioned within an 11/02/00 article entitled “Bidirectional Charge of Airway Responsiveness by Endogenous Cannabinoids” by Calignano et al. (p.96-101):
“Smoking marijuana or administration of their primary active constituent, THC, may exert potent dilating effects on human airways. However the physiological value of this observation and it is potential therapeutic value are hidden because some asthmatic patients react to these compounds having a peculiar bronchospasm [constriction from the airways from the lung] .
The systems underlying these contrasting reactions remain conflicting. Ideas reveal that endogenous cannabinoid anandamide puts dual effects on bronchial responsiveness in rats: it strongly suppresses bronchospasm and cough evoked through the chemical irritant, capsaicin, but causes bronchospasm once the rigid tone exerted through the vagus nerve is taken away.”
(November 2, 2000) Character
Daniele Piomelli, Ph.D., a professor in the College of California at Irvine, told Reuters in 2000:
“We believe that by focusing on cannabinoid receptors within the upper airways we are able to control coughs in many conditions…That’s important since most remedies presently available essentially act around the brain cough center, a little region from the brain that’s the prospective for codeine and other alike drugs .”
(2000) Daniele Piomelli, .D.
The American Journal of Respiratory system and demanding Care Medicine printed a 1975 (Volume 112) article by Jesse P. Tashkin, M.D. entitled “Effects of Smoked Marijuana in Experimentally Caused Bronchial asthma,” that mentioned:
” After exercise caused bronchospasm, [exercise-caused bronchial asthma] placebo marijuana and saline were then gradual recovery throughout 30 to 60 min, whereas 2. percent marijuana…caused an instantaneous turnaround of exercise-caused bronchial asthma and hyperinflation.”
(1975) American Journal of Respiratory system and demanding Care Medicine
The Brand New England Journal of drugs, a peer-examined medical journal, released a 1973 study entitled “Single-Dose Effect of Marihuana Smoke. Bronchial Dynamics and Respiratory system-Center Sensitivity in Normal Subjects,” by L. Vachon et al., that mentioned:
“Marihuana smoke, unlike tobacco smoke, causes bronchodilatation [growth of the environment passages] instead of bronchoconstriction [thinning from the airways] and, unlike opiates, doesn’t cause central respiratory system depression.
(1973) Colonial Journal of drugs
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