Cannitrol – Cannabis Control Agent

Marijuana news from around the world


Canadian Researchers Confirm Tetrahydrocannabinol (THC) Impedes Weight Gain

According to a recent study published in the PLOS ONE journal, small daily doses of THC prevents weight gain in lab mice fed a typical American diet – one that’s high in fat. Providing a sliver of hypothetical hope for the 78.6 million U.S. adults who suffer from obesity, a group of Canadian researchers looked […]

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Marijuana May be Able to Help Weight Loss and Diabetes

marijuana helps obesity diabetes

New study findings are constantly providing us with surprising news regarding the potential of medical marijuana.  The question we have to start asking is why are we still shocked to hear about these developments.  No other treatment available has demonstrated such a wide variety of applications.  Marijuana is producing results in areas that have baffled doctors and scientists.  Recently we learned that cannabis appears to posses the potential to help combat the spreading of the AIDS virus.  Additionally, new information is showing much promise for marijuana helping victims of PTSD and schizophrenia, two conditions where research has not been able to yield quality treatments.  This of course, is beautifully combined with the older and more well known applications of medical marijuana such as pain and nausea.

New research actually shows that marijuana may be helpful in an area that could seem silly if only analyzed from the surface.  While smoked cannabis is known for appetite stimulation (or the munchies as its more commonly referred as) GW Pharmaceuticals has found that two specific cannabinoids may be useful in appetite suppression and weight loss.  Cannabidiol (more commonly referred to as CBD) and THCV (a homologue of THC) could help burn calories and reduce hunger.  In tests, GW Pharmaceuticals found that animals introduced to the two cannabinoids displayed a boost in metabolic rates and fat burning.   Professor Mike Cawthorne, who has been conducting the trials and director of metabolic research at the University of Buckingham  said “Overall, it seems these molecules increase energy expenditure in the cells of the body by increasing the metabolism.”

This research builds on previous findings that the two cannabinoids were also effective in treating animals with type 2 diabetes.  The two studies provide hope for a new avenue of treatment for heart disease, stroke and other conditions that can result from weight gain and a breakdown of the metabolism.  Dr. Steph Wright, director of Research and Development at GW Pharmaceuticals agreed and recently said “We are interested in how these drugs effect the fat distribution and utilization in the body as a treatment for metabolic diseases.”

The pursuit of a magic weight loss pill has seemed as daunting as discovering the fountain of youth or spotting a unicorn.  However this quest is usually undertaken for cosmetic reasons and not always to improve health.  In either case, America’s obesity epidemic has reached dangerous levels with new and younger generations already dependent upon processed and unhealthy foods.  New research is confirming that cannabis is not taking lives, but may hold the potential for saving lives.

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Endocannabinoids in diet and weight problems


The Endocannabinoid system is an essential part of the body, controlling most of the others that individuals depend on.  Recent research have recommended it might be critical in assisting to deal with the increasing epidemic of weight problems and diabetes.  Both of these conditions, triggered with a myriad factors, have a massive toll on your body, frequently ending (as eventually everything does) in dying!  Within the last couple of years there’s been an enormous public outcry within the weight problems epidemic, with estimations declaring that certain in three People in america are obese and 1 in 5 youngsters are obese too.  Diabetes is frequently associated with weight problems, but that’s not necessarily the situation.  It’s a serious disease, directly accountable for killing over 70,000 People in america in 2007 and adding to 160,000 others.

The endocannabinoid system can sort out strategy to these conditions due to the way they help regulate your body’s energy intake and storage of calories in addition to hunger.  Whenever a person’s bloodstream sugar is not high enough, or they are stomach is empty, your brain transmits signals notifying them that they must eat. In early 2000’s, as scientists discovered the ties from the ECS towards the GI system, they observed that obstructing cannabinoid receptors assisted moderate urges and hunger permitting individuals to slim down.  This breakthrough brought towards the development and purchase from the drug Rimonabant.  It’s an inverse antagonist for that CB1 receptor which, in concern to hunger, blocks appetite.  Additionally, it creates glucose and fat metabolic process, which could either make the body to lose more energy, or store more.  Initially, this drug was praised like a success because test subjects and patients around the open market dropped a few pounds by using this drug.

However, there have been adverse unwanted effects, which many experts feel should happen to be foreseen.  For several years, researchers were conscious that cannabinoids effects were felt through the body. Apparently, the Rimonabant scientists had forgot to do complete studies on mental effects, additionally to physiological ones.  After under 3 years, Rimonabant’s unwanted effects grew to become well-known and it is approval was suspended by both Food and drug administration and EMEA (European Medications Agency).  By obstructing CB1 receptors the drug labored miracles on appetite, it had strong effects around the psyche.  Many patients experienced from insomnia, severe depression and suicidal ideas.  This victory against weight problems would be a double-edged sword, cutting weight and human happiness.  Although it ultimately unsuccessful, doctors have discovered much more about a persons body and mind.  So that they might not make that mistake again while searching for new remedies.

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The Endocannabinoid System


The Endocannabinoid System

Today we take time to inspect the Endocannabinoid system (ECS).  Whuh? Yes, after many years of research around the Cannabis plant, researchers recognized that the body (really most vertebrates or even a couple of invertebrates too) come with an organs and circulatory system that creates chemicals similar in structure and effect as individuals based in the world’s most versatile plant.  In 1964, ?9-tetrahydrocannabinol (THC) was isolated and thought as the active chemical in marijuana that triggers individuals to get high.  Ever since then, discoveries in chemistry and biology have brought to several breakthroughs about intricacies from the human body and mind.  Actually, you could reason that marijuana itself has spurred a larger knowledge of ourselves.  It works out that endocannabinoids are complex molecules that act at intercellular level on most of the body’s systems.  They’re transmitters that act on receptors in your body, “Endocannabinoid receptors are highly expressed within the brain, and also have been also present in organs and tissue from the body involved with energy homeostasis, for example adipose tissue, liver, intestinal tract, and skeletal muscle.” We began off considering nerve effects also it works out they’re type in energy regulation, body fat storage, memory and discomfort management and can also have an affect on fertility.  You will find several established cannabinoids and scientists are finding brand new ones his or her projects continue.  Although researchers have been studying cannabinoids for several years, the very first endocannabinoid wasn’t discovered and isolated before the early 1990’s,  Anandimide (arachidonoyl ethanolamide, AEA). Another chemical 2-Arachindonoylglycerol (2-AG) was referred to in 1994.

AEA’s effects could be observed in the mind in addition to peripheral systems, whereas 2-AG exists in high levels within the nervous system.  Presently the are three other recognized endogenous cannabinoids 2-arachidonyl glyceryl ether (noladin ether), virodhamine, along with the lately-discovered N-arachidonoyl-dopamine (NADA).  These chemicals float around our physiques, launched as necessary and do something about receptor sites CB1 and CB2.  The body is really a remarkably complex system that relays signals throughout itself using a number of techniques.  Basically, the body is a huge sodium pump that utilizes electrochemical stimulation to effect changes based on stimuli.  Some signals are relayed over nerves, firing electric. Others depend on these chemicals known as chemicals to complete the job.  To be able to keep your chaos low, a number of these chemicals act only in specific sites.  Think about it as being a number of locks and secrets.  To be able to prevent AEA from leading to responses inside your brain and stomach and toes simultaneously, it may only open doorways to particular areas like CB1 and CB2 sites.  The neurochemicals are furnished with some secrets that unlock specific doorways.

CB1 receptors are based in the brain, adipose (fatty tissue), liver, muscles, GI tract and pancreas.  Studies have proven that it’s integral to energy management and food and calorie consumption.  It accounts for impacting on hunger and appetite urges (munchies) and hunger satiety and palatability.  So, the activation of CB1 can trigger individuals urges for sweets while intoxicated by marijuana.  Additionally, it may incite hunger in patients whose illnesses cause appetite loss, or it may negate hunger and assist with weight reduction.  Focusing on how these chemicals operate in our physiques can result in doctors dealing with an array of illnesses from weight problems, anorexia, diabetes, and help chemotherapy patients.  New research has says adipose tissue is integral to energy management and putting on weight/loss.  Future remedies may benefit individuals with (or who’re vulnerable to) diabetes and weight problems.

CB2 receptor sites are located in high concentration within the brain and peripheral nervous systems, intestinal and natureal defenses.  By learning cannabinoids trigger reactions within scalping strategies we’ll have the ability to treat many troublesome illnesses.  Crohn’s disease and ulcerative colitis are a couple of very debilitating GI illnesses which have basis in immune response.  To put it simply, your body responds adversely to a lot of stimuli and attacks itself, leading to massive inflammation and attacking your personal organs.  By unleashing the strategies of these chemicals doctors will have the ability to treat these awful conditions and return quality of existence to suffering patients.

Case a newbie as to the science can perform once we gain further knowledge of these chemicals and our physiques.  It’s amazing to consider that many of these fields of research were opened up up through the cannabis plant.  The majority of it’s because of the efforts from the medicinal marijuana movement.  1000’s of doctors, researchers and scientists have devoted themselves to growing our understanding. With the aid of countless active supporters pushing for brand new laws and regulations and grants or loans we are able to continue this effort.  You never know what enlightenment is going to be based in the a long time?

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The Entire Year in Review


As you may know, 2011 would be a wild ride year for marijuana reform.  While there have been much talked about occasions like the Federal raids in California and Montana, there have been also many positive developments.  Allows recap the lengthy year:


We found that indoor marijuana growing accounts for approximately 1% from the U . s . States overall electric consumption.  This interesting fact will hopefully cause us to become eco-friendly, about being eco-friendly.  Get more information at more.


Medicinal Marijuana formally surpassed the A Million offered mark.  What is the news was a watch opener for a lot of and shows that it’s no more a fringe group.  Take a look at our previous coverage.


While claims were already available regarding marijuana’s benefits toward helping with Post traumatic stress disorder, official studies launched confirmed this.  Because of so many soldiers yet others going through distressing occasions, what is the news was heralded.  Take a look at our article about this problem.


Israel introduced that they are likely to significantly improve their medicinal marijuana program.  The best minister’s office designed a statement we frantically are awaiting within the U . s . States, “The Cabinet today approved plans and supervision concerning the way to obtain cannabis for medical and research uses. This really is in recognition the medical utilization of cannabis is essential in some cases. The Ministry will – in coordination using the Israel Police and also the Israel Anti-Drug Authority – oversee this and you’ll be accountable for supplies from imports and native cultivation.”  Additional coverage.


This season provided us positive news regarding medicinal marijuana states visiting a significant decrease in DWI’s and overall traffic deaths.  The entire year also demonstrated more teens are trying to find marijuana, but it’s a general trend and no greater in states with legalized medical cannabis.  More the following.


Holland made the decision to outlaw marijuana sales to vacationers.  They raided the still legal High Occasions Cannabis Cup.  They postponed the brand new limited laws and regulations.  Now they don’t appear sure.  Was a fascinating year for Amsterdam as you would expect, we’re certainly confused.

In a lot of ways, Colorado demonstrated us that medicinal marijuana could be controlled, which condition government will really attempt to safeguard patients.  Colorado released the very first ever condition license for medicinal marijuana.


New Approach Washington come up with the very best and many much talked about legal cast with former and current U.S. lawyers and idol judges, within their efforts to possess marijuana controlled like alcohol.  Take a look at more


Delaware approved their medicinal marijuana program.  Take a look at more about that.


Many states including New You are able to and Ohio have medicinal marijuana bills pending.  Here’s more about pending states.


We discovered that marijuana use might help to combat weight problems and it is generally utilized by individuals with greater intelligence.


We’d quite an eventful political year for marijuana.  Candidates expressed their sights on marijuana and Newt Gingrich stole the head lines together with his comments.  Ron Paul supported his previous claims and Gary Manley, the so known as “marijuana candidate” was excluded from debates.  Ron Paul also became a member of Barney Frank yet others by presenting legislation that will legitimize the with tax breaks for care providers and solid legal status.


2011 saw marijuana’s acceptance achieve its modern high water mark.  Polls show roughly 50% of the nation is perfect for legalisation and as much as 85% support medicinal marijuana.  Very couple of if any political issues come with an 85% consensus.  Read this article.

Sadly, the unsuccessful fight against drugs switched 40 this year.  A lot on the planet has transformed since that time, but Richard Nixon’s Fight Against Drugs remains a continuing.


Sythetic Marijuana put their hands up on everyone’s radar.  2011 saw many cities attempt to regulate the underground community, possibly not enough past too far.

Copenhagen made the decision they no more wanted a underground community for marijuana and required major steps toward legally controlling it. Take a look at our coverage.


Calls were noisy and obvious for any deleting of marijuana.  Two prominent governors lead the charge.


Michigan citizens demonstrated they’d not buckle when confronted with the infamous anti-marijuana condition Attorney General, Bill Schuette.  Not just did Kalamazoo voters make marijuana enforcement its cheapest priority, they’re also on the road to voting on repealing marijuana prohibition.


Regrettably, California’s earliest dispensary, Marin Alliance For Medicinal Marijuana Closed it’s doorways.


We can’t wait to know what you think regarding your ideas regarding 2011.  Leave us comments on these tales or make reference to highlights that didn’t appear here.  Marijuana.internet is searching toward talking with you.  Be safe while you celebrate 2012.

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Marijuana Myth Busters


Marijuana Myth Busters

Does smoking pot cause you to body fat?

Some patients would agree that marijuana increases appetite, it ought to follow that cannabis customers may be overweight than nonusers.  50,000 marijuana customers say otherwise.

In research conducted recently through the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) marijuana people who smoke were in comparison to nonsmokers.  Laptop computer discovered that 22 to a quarter of individuals who don’t smoke pot were obese, while only 16 to 17 % of cannabis customers were obese.   As measured by body mass index (Body mass index), cannabis customers were in better shape than nonusers.

The scientists were so surprised at their findings they went the research two times, after meeting with 50,000 subjects the outcomes were the same—marijuana people who smoke were less inclined to be obese.

Even though the reasons aren’t obvious, marijuana people who smoke are less inclined to be obese than nonsmokers.  Another myth about marijuana busted.  Next?

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Medical Marijuana Decreasing Obesity?


Terrible nutrition choices surround us. Health has given way to convenience and the American lifestyle is one that easily induces obesity. Constantly eating out and a lack of proper exercise have resulted in an overweight nation. Obesity rates have been on the rise over the last several decades and currently, over one third of Americans fall into this category.

The search for a magical weight loss solution has been coveted almost as much as the Holy Grail. Unfortunately, many of the pills have turned out to either not work well and/or cause serious side effects. Sanofi-Aventis’ Rimanabant initially had high hopes only to have to FDA decline approval for the drug due to concerns over increased depression and suicidal behavior. Other weight loss drugs have also faced their demise by the hands of the FDA. Meridia was pulled from the market last year due to an increased risk of heart attack and stroke.

Recently, there has been more positive news on a potential weight loss product. A study conducted by Dr. Yann Le Strat which was published in The American Journal of Epidemiology has discovered a link between lower obesity rates and marijuana use. The study does not provide concrete conclusions on exactly why this has occurred, but the findings are interesting. There are lifestyle factors that could also contribute to weight loss. Perhaps cannabis users eat less or are more active than stereotypes would suggest.

The recent study linking marijuana use to lower obesity does not necessarily solve America’s weight problem. However, with more research and a full understanding of why marijuana users are slimmer, we may be able to draw some helpful tips on losing weight in the future. With the side effects and high costs associated with dietary prescription pills, this link deserves further examination.

For more information, see: | Marijuana Slims? Why Pot Smokers Are Less Obese | The Diet Pill Dillema | Setbacks in Diet Pill Study



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